Ageing and endurance training effects on quantity and quality of pulmonary vascular bed in healthy men

François-Denis Desgorces (1, 2, 3) , Jean-François Toussaint (1, 2, 3) , Ghanima Al Dandachi (4) , Cécile Londner (4) , Aurore Caumont-Prim (4) , Laurent Plantier (4, 3) , Brigitte Chevalier-Bidaud (4) , Christophe Delclaux (4, 3, 5)

1 INSEP - Institut national du sport, de l'expertise et de la performance
2 IRMES - EA 7329 - Institut de recherche biomédicale et d’épidémiologie du sport
3 UPD5 Médecine - Université Paris Descartes - Faculté de Médecine
4 HEGP - Hôpital Européen Georges Pompidou [APHP]
5 EA 2511 - Mucoviscidose et bronchopathies chroniques : biopathologie et phénotypes cliniques

It has recently been demonstrated that in healthy individuals, peak oxygen consumption is associated with a greater pulmonary capillary blood volume and a more distensible pulmonary circulation. Our cross-sectional study suggests that, in healthy men aged 20 to 60 years (n = 63), endurance sport practice (vigorous-intensity domain of the International Physical Activity Questionnaire) is associated with better quantity (pulmonary capillary blood volume) and quality (slope of increase in lung diffusion for carbon monoxide on exercise) of the pulmonary vascular bed, partly counterbalancing the deleterious effects of ageing, which remains to be demonstrated in a prospective longitudinal design.

Mots clés: Physical activity; Exercise; Capillary blood volume; Lung diffusion Findings

Domaines: Sciences de l'Homme et Société; Sport; Physiologie du sport

François-Denis Desgorces, Jean-François Toussaint, Ghanima Al Dandachi, Cécile Londner, Aurore Caumont-Prim, et al.. Ageing and endurance training effects on quantity and quality of pulmonary vascular bed in healthy men. Respiratory Research, 2014, 15, pp.8. ⟨10.1186/1465-9921-15-8⟩. ⟨hal-01768375⟩